| 7. Round | 29/02/2020 | Club Nacional | - | Club Olimpia | 1:0 | ||||
| 8. Round | 06/03/2020 | Club Nacional | - | Cerro Porteño | 0:0 | ||||
| 11. Round | 01/08/2020 | Sol de América | - | Club Nacional | 1:1 | ||||
| 12. Round | 07/08/2020 | Guaireña FC | - | Club Nacional | 0:0 | ||||
| 13. Round | 11/08/2020 | Club Nacional | - | General Díaz | 3:0 |  |
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| 15. Round | 21/08/2020 | Club Nacional | - | San Lorenzo | 2:0 | |
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| 16. Round | 25/08/2020 | Guaraní | - | Club Nacional | 1:0 | ||||
| 18. Round | 06/09/2020 | Club Olimpia | - | Club Nacional | 4:0 | ||||
| 19. Round | 15/09/2020 | Cerro Porteño | - | Club Nacional | 1:0 | ||||
| 20. Round | 22/09/2020 | Club Nacional | - | River Plate | 1:2 |
Paraguay