| 8. Round | 13/11/2021 | AS Saint-Étienne [Women] | - | FC Fleury 91 [Women] | 0:4 |  |
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| 9. Round | 20/11/2021 | FC Fleury 91 [Women] | - | EA Guingamp [Women] | 6:2 | ||||
| 10. Round | 05/12/2021 | Olympique Lyonnais [Women] | - | FC Fleury 91 [Women] | 4:0 |  |
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| 11. Round | 12/12/2021 | FC Fleury 91 [Women] | - | GPSO 92 Issy [Women] | 1:0 | ||||
| 12. Round | 15/01/2022 | Stade de Reims [Women] | - | FC Fleury 91 [Women] | 0:1 | |
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| 14. Round | 04/02/2022 | FC Fleury 91 [Women] | - | Montpellier HSC [Women] | 1:0 | ||||
| 15. Round | 27/02/2022 | FC Fleury 91 [Women] | - | Paris Saint-Germain [Women] | 0:4 | ||||
| 16. Round | 11/03/2022 | Paris FC [Women] | - | FC Fleury 91 [Women] | 3:1 | ||||
| 17. Round | 20/03/2022 | FC Fleury 91 [Women] | - | Girondins Bordeaux [Women] | 2:0 | |
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| 18. Round | 02/04/2022 | ASJ Soyaux [Women] | - | FC Fleury 91 [Women] | 0:1 | ||||
| 19. Round | 17/04/2022 | FC Fleury 91 [Women] | - | Olympique Lyonnais [Women] | 1:2 | |
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| 20. Round | 07/05/2022 | GPSO 92 Issy [Women] | - | FC Fleury 91 [Women] | 0:5 | |
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| 21. Round | 28/05/2022 | FC Fleury 91 [Women] | - | AS Saint-Étienne [Women] | 4:2 | ||||
| 22. Round | 01/06/2022 | EA Guingamp [Women] | - | FC Fleury 91 [Women] | 0:3 | |
Ivory Coast