| 2. Round | 08/07/2022 | Club Tijuana [U20] | - | FC Juárez [U20] | 1:1 | ||||
| 9. Round | 17/08/2022 | Cruz Azul [U20] | - | Club Tijuana [U20] | 0:1 |  |
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| 10. Round | 20/08/2022 | Gallos Blancos [U20] | - | Club Tijuana [U20] | 1:1 | ||||
| 16. Round | 25/08/2022 | Club Tijuana [U20] | - | Santos Laguna [U20] | 1:1 | ||||
| 11. Round | 28/08/2022 | Club Tijuana [U20] | - | CF Monterrey [U20] | 1:1 | ||||
| 12. Round | 01/09/2022 | Atlético San Luis [U20] | - | Club Tijuana [U20] | 3:2 | |
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| 13. Round | 07/09/2022 | Club Tijuana [U20] | - | Deportivo Guadalajara [U20] | 1:1 | ||||
| 14. Round | 11/09/2022 | CF Pachuca [U20] | - | Club Tijuana [U20] | 4:0 | ||||
| 15. Round | 18/09/2022 | Club Tijuana [U20] | - | Club Necaxa [U20] | 2:3 | |
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| 3. Round | 28/09/2022 | UANL Tigres [U20] | - | Club Tijuana [U20] | 3:0 |
USA
Mexico