| 5. Round | 26/09/2021 | SAS Épinal [Youth B] | - | AS Nancy Lorraine [Youth B] | 0:3 | ||||
| 11. Round | 21/11/2021 | SAS Épinal [Youth B] | - | FC Metz [Youth B] | 0:5 | ||||
| 12. Round | 28/11/2021 | Olympique Lyonnais [Youth B] | - | SAS Épinal [Youth B] | 5:0 | ||||
| 18. Round | 06/03/2022 | SAS Épinal [Youth B] | - | RC Strasbourg [Youth B] | 0:6 | ||||
| 20. Round | 20/03/2022 | SAS Épinal [Youth B] | - | FC Bourg-Péronnas [Youth B] | 1:1 | ||||
| 23. Round | 10/04/2022 | FC Metz [Youth B] | - | SAS Épinal [Youth B] | 0:2 | ||||
| 24. Round | 17/04/2022 | SAS Épinal [Youth B] | - | Olympique Lyonnais [Youth B] | 1:5 | ||||
| 25. Round | 01/05/2022 | FC Sochaux [Youth B] | - | SAS Épinal [Youth B] | 4:1 |
France