1. Round | 11/09/2021 | Cerro Largo | - | Nacional | 0:3 dec. | ||||
2. Round | 18/09/2021 | Cerrito | - | Cerro Largo | 1:1 | ||||
4. Round | 02/10/2021 | River Plate | - | Cerro Largo | 0:4 | ||||
6. Round | 17/10/2021 | Cerro Largo | - | Progreso | 1:0 | ||||
7. Round | 21/10/2021 | Sud América | - | Cerro Largo | 0:0 | ||||
13. Round | 23/11/2021 | Peñarol | - | Cerro Largo | 2:2 | ||||
15. Round | 05/12/2021 | Villa Española | - | Cerro Largo | 1:1 |