| 4. Round | 03/09/2022 | Defensor Sporting | - | Montevideo Wanderers | 1:0 | ||||
| 7. Round | 10/09/2022 | Montevideo Wanderers | - | Danubio | 0:3 | ||||
| 8. Round | 13/09/2022 | Deportivo Maldonado | - | Montevideo Wanderers | 1:0 | ||||
| 9. Round | 17/09/2022 | Montevideo Wanderers | - | Rentistas | 1:0 | ||||
| 14. Round | 17/10/2022 | Montevideo Wanderers | - | Plaza Colonia | 2:1 |  |
Uruguay