| 1. Round | 15/05/2021 | Montevideo City Torque | - | Sud América | 0:1 | ||||
| 2. Round | 23/05/2021 | Plaza Colonia | - | Montevideo City Torque | 1:0 | ||||
| 4. Round | 06/06/2021 | Boston River | - | Montevideo City Torque | 1:2 |  |
|||
| 5. Round | 11/06/2021 | Montevideo City Torque | - | Montevideo Wanderers | 2:1 | ||||
| 6. Round | 18/06/2021 | Rentistas | - | Montevideo City Torque | 0:2 | ||||
| 8. Round | 28/06/2021 | Montevideo City Torque | - | Deportivo Maldonado | 2:3 | ||||
| 10. Round | 11/07/2021 | Montevideo City Torque | - | Nacional | 3:0 | ||||
| 11. Round | 24/07/2021 | Montevideo City Torque | - | Cerrito | 0:2 | ||||
| 12. Round | 01/08/2021 | Montevideo City Torque | - | Liverpool | 0:3 | ||||
| 13. Round | 07/08/2021 | River Plate | - | Montevideo City Torque | 3:3 |  |
|||
| 14. Round | 15/08/2021 | Montevideo City Torque | - | Cerro Largo | 3:0 | |
|||
| 15. Round | 20/08/2021 | Progreso | - | Montevideo City Torque | 1:4 |
Uruguay