| 17. Round | 23/06/2021 | Chacaritas FC | - | Guayaquil SC | 2:3 |  |
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| 30. Round | 01/09/2021 | Gualaceo SC | - | Chacaritas FC | 0:1 | ||||
| 31. Round | 08/09/2021 | Chacaritas FC | - | El Nacional | 1:1 | ||||
| 33. Round | 22/09/2021 | Chacaritas FC | - | Guayaquil SC | 4:1 | ||||
| 34. Round | 29/09/2021 | Cumbayá | - | Chacaritas FC | 0:2 | ||||
| 35. Round | 06/10/2021 | Liga de Portoviejo | - | Chacaritas FC | 1:0 |
Ecuador