| 2. Round | 12/02/2017 | Boston River | - | River Plate | 2:0 |  |
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| 3. Round | 19/02/2017 | Peñarol | - | Boston River | 0:0 | ||||
| 4. Round | 25/02/2017 | Boston River | - | Racing | 0:1 | ||||
| 5. Round | 05/03/2017 | El Tanque Sisley | - | Boston River | 1:0 | ||||
| 6. Round | 12/03/2017 | Boston River | - | Liverpool | 3:1 | ||||
| 12. Round | 23/04/2017 | Defensor Sporting | - | Boston River | 1:0 | ||||
| 13. Round | 29/04/2017 | Boston River | - | Sud América | 1:0 | ||||
| 15. Round | 14/05/2017 | Boston River | - | Danubio | 0:3 |
Uruguay