| 1. Round | 10/07/2021 | Veles Moskva | - | Enisey Krasnoyarsk | 1:0 | ||||
| 2. Round | 17/07/2021 | Enisey Krasnoyarsk | - | Kuban Krasnodar | 2:2 | ||||
| 4. Round | 31/07/2021 | Enisey Krasnoyarsk | - | Alania Vladikavkaz | 0:3 | ||||
| 7. Round | 21/08/2021 | SKA-Khabarovsk | - | Enisey Krasnoyarsk | 4:3 | ||||
| 9. Round | 05/09/2021 | Metallurg Lipetsk | - | Enisey Krasnoyarsk | 0:2 | ||||
| 13. Round | 25/09/2021 | FK Orenburg | - | Enisey Krasnoyarsk | 2:0 | ||||
| 14. Round | 29/09/2021 | Akron Tolyatti | - | Enisey Krasnoyarsk | 4:1 | ||||
| 15. Round | 03/10/2021 | FK Neftekhimik | - | Enisey Krasnoyarsk | 2:3 | ||||
| 25. Round | 27/11/2021 | Enisey Krasnoyarsk | - | SKA-Khabarovsk | 3:1 | ||||
| 38. Round | 21/05/2022 | Enisey Krasnoyarsk | - | Veles Moskva | 3:2 |
Russia