| 7. Round | 11/09/2021 | SShOR Zenit [Youth] | - | FK Rostov [Youth] | 0:2 | ||||
| 11. Round | 16/10/2021 | SShOR Zenit [Youth] | - | Zenit St. Petersburg [Youth] | 1:1 | ||||
| 12. Round | 23/10/2021 | SShOR Zenit [Youth] | - | FK Saturn [Youth] | 0:2 |  |
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| 15. Round | 20/11/2021 | Dinamo Moskva [Youth] | - | SShOR Zenit [Youth] | 1:2 |  |
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| 16. Round | 27/11/2021 | CSKA Moskva [Youth] | - | SShOR Zenit [Youth] | 3:1 | |
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| 17. Round | 06/03/2022 | Lokomotiv Moskva [Youth] | - | SShOR Zenit [Youth] | 3:2 | ||||
| 18. Round | 12/03/2022 | FK Strogino Moskva [Youth] | - | SShOR Zenit [Youth] | 3:1 | |
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| 13. Round | 19/03/2022 | FK Krasnodar [Youth] | - | SShOR Zenit [Youth] | 2:1 | |
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| 20. Round | 09/04/2022 | FK Rostov [Youth] | - | SShOR Zenit [Youth] | 0:1 | |
Russia