| 3. Round | 03/08/2014 | CF Monterrey | - | Santos Laguna | 0:0 | ||||
| 4. Round | 10/08/2014 | Santos Laguna | - | Gallos Blancos | 2:3 | ||||
| 6. Round | 23/08/2014 | Santos Laguna | - | Deportivo Toluca | 3:0 | ||||
| 10. Round | 27/09/2014 | Santos Laguna | - | CF América | 1:4 | ||||
| 11. Round | 01/10/2014 | UANL Tigres | - | Santos Laguna | 1:1 |  |
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| 12. Round | 05/10/2014 | Santos Laguna | - | Monarcas Morelia | 2:2 | ||||
| 13. Round | 19/10/2014 | Chiapas FC | - | Santos Laguna | 2:0 | ||||
| 15. Round | 02/11/2014 | Leones Negros | - | Santos Laguna | 1:1 |
Mexico