| 1. Round | 08/08/2021 | US Hostert | - | FC Rodange 91 | 3:1 | ||||
| 2. Round | 14/08/2021 | FC Rodange 91 | - | RFCU Luxemburg | 0:1 | ||||
| 3. Round | 23/08/2021 | Union Titus Pétange | - | FC Rodange 91 | 3:0 |  |
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| 4. Round | 29/08/2021 | FC Rodange 91 | - | US Mondorf | 1:1 | ||||
| 5. Round | 12/09/2021 | Etzella Ettelbruck | - | FC Rodange 91 | 3:0 | ||||
| 8. Round | 26/09/2021 | FC Rodange 91 | - | CS FOLA Esch | 1:2 | ||||
| 9. Round | 17/10/2021 | UNA Strassen | - | FC Rodange 91 | 4:1 | ||||
| 10. Round | 24/10/2021 | FC Rodange 91 | - | Swift Hesperange | 2:3 | |
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| 11. Round | 05/11/2021 | FC Rodange 91 | - | Progrès Niedercorn | 0:1 | ||||
| 12. Round | 21/11/2021 | RM Hamm Benfica | - | FC Rodange 91 | 1:2 | ||||
| 13. Round | 28/11/2021 | FC Rodange 91 | - | FC Wiltz 71 | 2:0 | |
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| 14. Round | 04/12/2021 | F91 Dudelange | - | FC Rodange 91 | 5:1 | |
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| 15. Round | 12/12/2021 | FC Rodange 91 | - | Jeunesse Esch | 1:4 | ||||
| 17. Round | 12/02/2022 | FC Rodange 91 | - | Union Titus Pétange | 0:4 | |
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| 19. Round | 27/02/2022 | FC Rodange 91 | - | Etzella Ettelbruck | 0:2 |
France