| 26. Round | 27/03/2022 | APS Zakynthos | - | PS Kalamata | 1:1 | ||||
| 27. Round | 30/03/2022 | Panathinaikos II | - | APS Zakynthos | 1:1 | ||||
| 28. Round | 03/04/2022 | APS Zakynthos | - | AE Karaiskakis | 2:0 |  |
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| 29. Round | 06/04/2022 | Ergotelis | - | APS Zakynthos | 1:0 | ||||
| 30. Round | 10/04/2022 | APS Zakynthos | - | Asteras Vlachioti | 1:1 | ||||
| 31. Round | 13/04/2022 | Diagoras FC | - | APS Zakynthos | 2:0 | ||||
| 34. Round | 01/05/2022 | OFI Ierapetra | - | APS Zakynthos | 5:1 |
Cameroon