| 5. Round | 22/03/2025 | Charlotte FC | - | San Jose Earthquakes | 4:1 | ||||
| 6. Round | 29/03/2025 | Colorado Rapids | - | Charlotte FC | 2:0 | ||||
| 7. Round | 05/04/2025 | Charlotte FC | - | Nashville SC | 2:1 | ||||
| 8. Round | 13/04/2025 | CF Montréal | - | Charlotte FC | 0:1 | ||||
| 9. Round | 20/04/2025 | Charlotte FC | - | San Diego FC | 3:0 | ||||
| 16. Round | 29/05/2025 | New York RB | - | Charlotte FC | 4:2 | ||||
| 17. Round | 01/06/2025 | Toronto FC | - | Charlotte FC | 0:2 |
France