| 3. Round | 30/09/2007 | Veria FC | - | Skoda Xanthi | 1:1 | ||||
| 4. Round | 07/10/2007 | Skoda Xanthi | - | Atromitos | 0:1 | ||||
| 5. Round | 21/10/2007 | Levadiakos | - | Skoda Xanthi | 2:1 | ||||
| 6. Round | 28/10/2007 | Skoda Xanthi | - | AEK Athen | 0:1 | ||||
| 10. Round | 01/12/2007 | Panathinaikos | - | Skoda Xanthi | 0:0 | ||||
| 11. Round | 09/12/2007 | Skoda Xanthi | - | OFI Heraklion | 1:0 | ||||
| 16. Round | 13/01/2008 | PAOK Saloniki | - | Skoda Xanthi | 0:1 | ||||
| 17. Round | 20/01/2008 | Asteras Tripolis | - | Skoda Xanthi | 0:0 | ||||
| 18. Round | 26/01/2008 | Skoda Xanthi | - | Veria FC | 2:0 | ||||
| 19. Round | 02/02/2008 | Atromitos | - | Skoda Xanthi | 2:3 | ||||
| 21. Round | 05/03/2008 | AEK Athen | - | Skoda Xanthi | 3:0 |  |
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| 24. Round | 09/03/2008 | Iraklis Saloniki | - | Skoda Xanthi | 1:1 | ||||
| 25. Round | 16/03/2008 | Skoda Xanthi | - | Panathinaikos | 3:2 | ||||
| 26. Round | 23/03/2008 | OFI Heraklion | - | Skoda Xanthi | 2:0 | ||||
| 30. Round | 20/04/2008 | Ergotelis | - | Skoda Xanthi | 2:0 |
Greece