| 21. Round | 13/03/2022 | Swift Hesperange | - | CS FOLA Esch | 1:1 | ||||
| 22. Round | 19/03/2022 | CS FOLA Esch | - | FC Rodange 91 | 8:0 | ||||
| 24. Round | 10/04/2022 | CS FOLA Esch | - | FC Wiltz 71 | 2:1 | ||||
| 28. Round | 07/05/2022 | CS FOLA Esch | - | RFCU Luxemburg | 2:0 |  |
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| 30. Round | 22/05/2022 | CS FOLA Esch | - | US Mondorf | 1:1 |
Luxembourg
Italy