| 1. Round | 19/07/2021 | Dinamo Bucureşti | - | FC Voluntari | 3:2 | ||||
| 2. Round | 26/07/2021 | FC Universitatea Craiova | - | Dinamo Bucureşti | 1:0 |  |
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| 3. Round | 02/08/2021 | Dinamo Bucureşti | - | Academica Clinceni | 3:1 | |
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| 4. Round | 08/08/2021 | Chindia Târgoviște | - | Dinamo Bucureşti | 1:0 | ||||
| 5. Round | 16/08/2021 | Dinamo Bucureşti | - | CS Mioveni | 0:1 | ||||
| 6. Round | 20/08/2021 | Farul Constanța | - | Dinamo Bucureşti | 3:0 | |
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| 8. Round | 12/09/2021 | FCSB | - | Dinamo Bucureşti | 6:0 |  |
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| 10. Round | 27/09/2021 | CS Universitatea Craiova | - | Dinamo Bucureşti | 5:0 | ||||
| 11. Round | 02/10/2021 | Dinamo Bucureşti | - | UTA Arad | 2:2 | |
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| 12. Round | 15/10/2021 | Gaz Metan Mediaş | - | Dinamo Bucureşti | 2:1 | |
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| 13. Round | 23/10/2021 | Dinamo Bucureşti | - | Rapid Bucureşti | 1:1 | ||||
| 16. Round | 22/11/2021 | FC Voluntari | - | Dinamo Bucureşti | 2:1 | ||||
| 18. Round | 03/12/2021 | Academica Clinceni | - | Dinamo Bucureşti | 1:0 | ||||
| 29. Round | 01/03/2022 | Dinamo Bucureşti | - | Sepsi OSK | 1:3 | ||||
| 30. Round | 06/03/2022 | CFR Cluj | - | Dinamo Bucureşti | 4:1 |  |
Romania