| 5. Round | 21/08/2022 | FK Legion Dynamo Makhachkala | - | FK Yessentuki | 3:1 | ||||
| 6. Round | 26/08/2022 | FK Yessentuki | - | Chernomorets Novorossisk | 1:2 | ||||
| 7. Round | 03/09/2022 | Dinamo Stavropol | - | FK Yessentuki | 0:0 | ||||
| 8. Round | 09/09/2022 | FK Yessentuki | - | FK SKA Rostov | 2:2 | ||||
| 9. Round | 18/09/2022 | FK Chayka | - | FK Yessentuki | 2:0 | ||||
| 10. Round | 25/09/2022 | FK Mashuk KMV | - | FK Yessentuki | 2:0 | ||||
| 11. Round | 30/09/2022 | FK Yessentuki | - | Forte Taganrog | 0:1 |  |
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| 12. Round | 08/10/2022 | Spartak Nalchik | - | FK Yessentuki | 1:0 | ||||
| 13. Round | 14/10/2022 | FK Yessentuki | - | Rotor Volgograd | 0:6 | ||||
| 14. Round | 21/10/2022 | Kuban-Holding Pavlovskaya | - | FK Yessentuki | 5:0 | |
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| 15. Round | 28/10/2022 | FK Yessentuki | - | Alania-2 Vladikavkaz | 0:3 | |
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| 16. Round | 04/11/2022 | FK Druzhba | - | FK Yessentuki | 4:0 | ||||
| 17. Round | 09/11/2022 | FK Yessentuki | - | FK Legion Dynamo Makhachkala | 0:7 |
Russia