| 10. Round | 11/09/2021 | FK Kamaz | - | FK Orenburg | 0:4 | ||||
| 11. Round | 15/09/2021 | Akron Tolyatti | - | FK Kamaz | 0:0 | ||||
| 12. Round | 19/09/2021 | FK Kamaz | - | FK Neftekhimik | 0:1 | ||||
| 13. Round | 25/09/2021 | Rotor Volgograd | - | FK Kamaz | 1:0 | ||||
| 14. Round | 29/09/2021 | Veles Moskva | - | FK Kamaz | 0:0 | ||||
| 15. Round | 03/10/2021 | FK Kamaz | - | FK Krasnodar 2 | 2:0 | ||||
| 16. Round | 09/10/2021 | Torpedo Moskva | - | FK Kamaz | 1:1 | ||||
| 17. Round | 13/10/2021 | FK Kamaz | - | Enisey Krasnoyarsk | 1:1 | ||||
| 18. Round | 17/10/2021 | Kuban Krasnodar | - | FK Kamaz | 1:0 |  |
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| 19. Round | 23/10/2021 | FK Kamaz | - | Spartak Moskva 2 | 4:1 | ||||
| 20. Round | 31/10/2021 | Tekstilshchik Ivanovo | - | FK Kamaz | 4:1 | ||||
| 21. Round | 06/11/2021 | FK Kamaz | - | Olimp-Dolgoprudny | 1:1 | ||||
| 22. Round | 13/11/2021 | SKA-Khabarovsk | - | FK Kamaz | 1:0 | ||||
| 23. Round | 17/11/2021 | FK Kamaz | - | Volgar Astrakhan | 0:0 | |
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| 24. Round | 21/11/2021 | Metallurg Lipetsk | - | FK Kamaz | 0:1 | ||||
| 25. Round | 27/11/2021 | Baltika Kaliningrad | - | FK Kamaz | 0:0 |
Russia