| 2. Round | 08/01/2022 | FC Châlonnais [Youth] | - | RC Strasbourg [Youth] | 0:5 |  |
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| 3. Round | 30/01/2022 | RC Strasbourg [Youth] | - | Montpellier HSC [Youth] | 5:4 pso | ||||
| Round of 16 | 19/02/2022 | RC Strasbourg [Youth] | - | US Avranches [Youth] | 2:1 | ||||
| Quarter-finals | 13/03/2022 | Olympique Lyonnais [Youth] | - | RC Strasbourg [Youth] | 2:0 |
France