| 15. Round | 08/01/2023 | SBV Excelsior | - | FC Groningen | 1:0 | ||||
| 16. Round | 15/01/2023 | FC Groningen | - | Feyenoord | 0:3 | ||||
| 18. Round | 26/01/2023 | FC Groningen | - | SC Cambuur | 0:1 |  |
|||
| 19. Round | 29/01/2023 | FC Volendam | - | FC Groningen | 3:2 | ||||
| 23. Round | 25/02/2023 | FC Groningen | - | SBV Excelsior | 3:0 | ||||
| 24. Round | 04/03/2023 | Feyenoord | - | FC Groningen | 1:0 | ||||
| 25. Round | 11/03/2023 | AZ Alkmaar | - | FC Groningen | 1:0 | ||||
| 29. Round | 15/04/2023 | RKC Waalwijk | - | FC Groningen | 2:1 | ||||
| 30. Round | 25/04/2023 | FC Groningen | - | NEC Nijmegen | 0:1 | ||||
| 31. Round | 07/05/2023 | Go Ahead Eagles | - | FC Groningen | 1:1 | ||||
| 32. Round | 16/05/2023 | FC Groningen | - | AFC Ajax | 2:3 | ||||
| 33. Round | 21/05/2023 | Vitesse | - | FC Groningen | 6:0 |
Netherlands