13. Round | 24/09/2021 | Central Córdoba SdE II | - | River Plate II | 1:2 | ||||
15. Round | 07/10/2021 | Banfield II | - | River Plate II | 2:0 | ||||
21. Round | 19/11/2021 | Platense II | - | River Plate II | 5:2 | ||||
22. Round | 23/11/2021 | River Plate II | - | Racing Club II | 1:2 | ||||
23. Round | 28/11/2021 | Rosario Central II | - | River Plate II | 2:0 | ||||
24. Round | 03/12/2021 | River Plate II | - | Defensa y Justicia II | 2:1 | ||||
25. Round | 10/12/2021 | Atlético Tucumán II | - | River Plate II | 1:1 |