| 4. Round | 08/07/2021 | Vancouver Whitecaps | - | Real Salt Lake | 0:4 | ||||
| 4. Round | 18/07/2021 | Vancouver Whitecaps | - | Los Angeles Galaxy | 2:1 | ||||
| 4. Round | 21/07/2021 | Vancouver Whitecaps | - | Houston Dynamo | 0:0 | ||||
| 4. Round | 25/07/2021 | Los Angeles FC | - | Vancouver Whitecaps | 2:2 | ||||
| 5. Round | 01/08/2021 | Vancouver Whitecaps | - | Minnesota United FC | 2:2 | ||||
| 6. Round | 05/09/2021 | Vancouver Whitecaps | - | Austin FC | 2:1 | ||||
| 7. Round | 10/10/2021 | Seattle Sounders | - | Vancouver Whitecaps | 4:1 |
Canada
Czech Republic