| 3. Round | 01/03/2022 | Santa Cruz | - | CD Magallanes | 1:2 | ||||
| 4. Round | 09/03/2022 | CD Magallanes | - | Universidad de Concepción | 1:0 | ||||
| 5. Round | 15/03/2022 | Deportes Iquique | - | CD Magallanes | 1:1 | ||||
| 6. Round | 23/03/2022 | CD Magallanes | - | Cobreloa | 2:1 | ||||
| 15. Round | 15/05/2022 | CD Magallanes | - | Deportes Copiapó | 1:0 | ||||
| 16. Round | 24/05/2022 | Rangers | - | CD Magallanes | 2:2 | ||||
| 17. Round | 29/05/2022 | CD Magallanes | - | Recoleta | 2:1 | ||||
| 18. Round | 03/07/2022 | Puerto Montt | - | CD Magallanes | 1:0 | ||||
| 20. Round | 16/07/2022 | CD Magallanes | - | Santa Cruz | 0:0 | ||||
| 21. Round | 24/07/2022 | Universidad de Concepción | - | CD Magallanes | 0:2 | ||||
| 23. Round | 06/08/2022 | Cobreloa | - | CD Magallanes | 1:0 | ||||
| 28. Round | 15/09/2022 | CD Magallanes | - | Santiago Morning | 1:1 | ||||
| 30. Round | 03/10/2022 | Unión San Felipe | - | CD Magallanes | 1:4 |  |
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| 31. Round | 09/10/2022 | CD Magallanes | - | Deportes Melipilla | 7:0 | |
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| 32. Round | 21/10/2022 | Deportes Copiapó | - | CD Magallanes | 2:2 | |
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| 33. Round | 23/10/2022 | CD Magallanes | - | Rangers | 2:0 | ||||
| 34. Round | 01/11/2022 | Recoleta | - | CD Magallanes | 0:2 |
Chile