| 1. Round | 08/07/2023 | Libertad | - | Club Nacional | 2:0 |  |
|||
| 2. Round | 18/07/2023 | Club Nacional | - | Tacuary | 1:1 | ||||
| 3. Round | 23/07/2023 | Club Olimpia | - | Club Nacional | 1:2 | |
|||
| 4. Round | 29/07/2023 | Guaraní | - | Club Nacional | 1:1 | ||||
| 5. Round | 06/08/2023 | Club Nacional | - | Guaireña FC | 2:0 | ||||
| 6. Round | 12/08/2023 | Sportivo Ameliano | - | Club Nacional | 2:0 | ||||
| 8. Round | 29/08/2023 | Resistencia SC | - | Club Nacional | 2:1 |  |
|||
| 9. Round | 04/09/2023 | Club Nacional | - | Sportivo Trinidense | 1:2 | |
|||
| 12. Round | 24/09/2023 | Club Nacional | - | Libertad | 2:3 | ||||
| 13. Round | 01/10/2023 | Tacuary | - | Club Nacional | 0:3 | ||||
| 15. Round | 18/10/2023 | Club Nacional | - | Guaraní | 4:0 | |
|||
| 16. Round | 22/10/2023 | Guaireña FC | - | Club Nacional | 0:0 | ||||
| 18. Round | 01/11/2023 | General Caballero DJLM | - | Club Nacional | 0:0 | |
|||
| 20. Round | 13/11/2023 | Sportivo Trinidense | - | Club Nacional | 1:1 | ||||
| 21. Round | 26/11/2023 | Club Nacional | - | Cerro Porteño | 1:1 |
Paraguay