| 5. Round | 23/09/2007 | SBV Excelsior | - | FC Groningen | 1:3 | ||||
| 6. Round | 29/09/2007 | FC Groningen | - | Sparta Rotterdam | 1:0 | ||||
| 11. Round | 11/11/2007 | Roda JC Kerkrade | - | FC Groningen | 5:1 | ||||
| 16. Round | 22/12/2007 | Heracles Almelo | - | FC Groningen | 1:2 | ||||
| 17. Round | 26/12/2007 | FC Groningen | - | PSV Eindhoven | 2:1 | ||||
| 18. Round | 29/12/2007 | Sparta Rotterdam | - | FC Groningen | 1:3 | ||||
| 19. Round | 12/01/2008 | FC Groningen | - | SBV Excelsior | 3:2 | ||||
| 20. Round | 20/01/2008 | FC Twente | - | FC Groningen | 3:1 | ||||
| 21. Round | 23/01/2008 | FC Groningen | - | NEC Nijmegen | 5:1 | ||||
| 27. Round | 02/03/2008 | FC Groningen | - | Heracles Almelo | 1:2 | ||||
| 28. Round | 08/03/2008 | Willem II | - | FC Groningen | 1:2 | ||||
| 29. Round | 14/03/2008 | FC Groningen | - | sc Heerenveen | 0:1 | ||||
| 30. Round | 22/03/2008 | PSV Eindhoven | - | FC Groningen | 3:0 | ||||
| 31. Round | 28/03/2008 | De Graafschap | - | FC Groningen | 1:1 | ||||
| 33. Round | 16/04/2008 | FC Groningen | - | AFC Ajax | 1:2 |
Slovenia