| 1. Round | 24/07/2021 | KV Kortrijk | - | RFC Seraing | 2:0 |  |
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| 2. Round | 01/08/2021 | Royal Antwerp FC | - | KV Kortrijk | 0:1 | ||||
| 3. Round | 07/08/2021 | KV Kortrijk | - | KRC Genk | 1:2 | ||||
| 4. Round | 14/08/2021 | Union Saint-Gilloise | - | KV Kortrijk | 2:0 | |
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| 19. Round | 14/12/2021 | KV Oostende | - | KV Kortrijk | 0:2 |
Belgium