| 9. Round | 13/11/2020 | Club Irapuato | - | Azores de Hidalgo | 5:0 | ||||
| 2. Round | 18/11/2020 | CD Cuautla | - | Club Irapuato | 1:3 | ||||
| 12. Round | 06/12/2020 | Club Irapuato | - | Club de Ciervos | 0:0 | ||||
| 16. Round | 30/01/2021 | Deportivo Dongu | - | Club Irapuato | 0:7 | ||||
| 26. Round | 09/04/2021 | Club Irapuato | - | Cañoneros Marina | 6:0 |
Argentina