| 8. Round | 29/08/2021 | Enisey Krasnoyarsk | - | Volgar Astrakhan | 2:2 | ||||
| 9. Round | 05/09/2021 | Metallurg Lipetsk | - | Enisey Krasnoyarsk | 0:2 | ||||
| 15. Round | 03/10/2021 | FK Neftekhimik | - | Enisey Krasnoyarsk | 2:3 |  |
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| 16. Round | 09/10/2021 | Enisey Krasnoyarsk | - | Rotor Volgograd | 1:1 | |
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| 17. Round | 13/10/2021 | FK Kamaz | - | Enisey Krasnoyarsk | 1:1 | ||||
| 22. Round | 13/11/2021 | Alania Vladikavkaz | - | Enisey Krasnoyarsk | 1:2 | ||||
| 23. Round | 17/11/2021 | Enisey Krasnoyarsk | - | Tekstilshchik Ivanovo | 3:0 | ||||
| 24. Round | 21/11/2021 | Olimp-Dolgoprudny | - | Enisey Krasnoyarsk | 0:0 |  |
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| 29. Round | 26/03/2022 | Enisey Krasnoyarsk | - | Fakel Voronezh | 2:1 | ||||
| 37. Round | 15/05/2022 | Enisey Krasnoyarsk | - | Torpedo Moskva | 0:1 |
Lithuania