| 1. Round | 13/08/2021 | NK Inter Zaprešić | - | NK Croatia Zmijavci | 0:0 | ||||
| 2. Round | 22/08/2021 | NK Croatia Zmijavci | - | NK Kustošija | 2:1 |  |
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| 3. Round | 29/08/2021 | NK BSK Bijelo Brdo | - | NK Croatia Zmijavci | 2:0 | ||||
| 4. Round | 10/09/2021 | NK Croatia Zmijavci | - | Dinamo Zagreb II | 2:2 | ||||
| 5. Round | 15/09/2021 | NK Solin | - | NK Croatia Zmijavci | 3:0 | ||||
| 6. Round | 19/09/2021 | NK Osijek II | - | NK Croatia Zmijavci | 1:2 | ||||
| 7. Round | 26/09/2021 | NK Croatia Zmijavci | - | NK Opatija | 3:0 | ||||
| 8. Round | 02/10/2021 | NK Varaždin | - | NK Croatia Zmijavci | 5:1 | ||||
| 9. Round | 17/10/2021 | NK Croatia Zmijavci | - | NK Rudeš | 1:0 | ||||
| 10. Round | 23/10/2021 | NK Jarun | - | NK Croatia Zmijavci | 2:3 |  |
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| 12. Round | 06/11/2021 | NK Dugopolje | - | NK Croatia Zmijavci | 1:2 | |
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| 13. Round | 21/11/2021 | NK Croatia Zmijavci | - | NK Dubrava | 0:1 | ||||
| 14. Round | 27/11/2021 | HNK Orijent Rijeka | - | NK Croatia Zmijavci | 3:2 | |
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| 15. Round | 05/12/2021 | NK Croatia Zmijavci | - | HNK Cibalia | 1:1 |
Croatia