| 2. Round | 18/09/2020 | VVV-Venlo | - | FC Utrecht | 1:1 | ||||
| 3. Round | 26/09/2020 | sc Heerenveen | - | VVV-Venlo | 1:0 | ||||
| 4. Round | 03/10/2020 | VVV-Venlo | - | ADO Den Haag | 1:2 | ||||
| 5. Round | 17/10/2020 | AZ Alkmaar | - | VVV-Venlo | 2:2 | ||||
| 14. Round | 22/12/2020 | PSV Eindhoven | - | VVV-Venlo | 4:1 | ||||
| 15. Round | 10/01/2021 | VVV-Venlo | - | Willem II | 2:1 | ||||
| 16. Round | 13/01/2021 | ADO Den Haag | - | VVV-Venlo | 1:4 |  |
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| 17. Round | 17/01/2021 | VVV-Venlo | - | sc Heerenveen | 1:1 | ||||
| 18. Round | 24/01/2021 | FC Twente | - | VVV-Venlo | 0:1 | ||||
| 28. Round | 03/04/2021 | VVV-Venlo | - | FC Groningen | 0:1 | ||||
| 29. Round | 11/04/2021 | VVV-Venlo | - | PSV Eindhoven | 0:2 | ||||
| 30. Round | 24/04/2021 | Sparta Rotterdam | - | VVV-Venlo | 2:0 | ||||
| 31. Round | 01/05/2021 | Heracles Almelo | - | VVV-Venlo | 4:0 | ||||
| 32. Round | 08/05/2021 | VVV-Venlo | - | RKC Waalwijk | 3:3 | ||||
| 34. Round | 16/05/2021 | VVV-Venlo | - | FC Emmen | 0:4 |
Netherlands
South Korea