| 1. Round | 23/02/2025 | Seattle Sounders | - | Charlotte FC | 2:2 | ||||
| 8. Round | 13/04/2025 | CF Montréal | - | Charlotte FC | 0:1 | ||||
| 10. Round | 27/04/2025 | Charlotte FC | - | New England Revolution | 0:1 | ||||
| 11. Round | 04/05/2025 | Columbus Crew | - | Charlotte FC | 4:2 | ||||
| 15. Round | 25/05/2025 | Charlotte FC | - | Columbus Crew | 3:2 | ||||
| 16. Round | 29/05/2025 | New York RB | - | Charlotte FC | 4:2 | ||||
| 18. Round | 15/06/2025 | Philadelphia Union | - | Charlotte FC | 2:1 | ||||
| 19. Round | 26/06/2025 | Sporting Kansas City | - | Charlotte FC | 2:1 |
England