| 1. Round | 26/07/2020 | Cruz Azul | - | Santos Laguna | 2:0 | ||||
| 2. Round | 03/08/2020 | Santos Laguna | - | Deportivo Guadalajara | 2:0 | ||||
| 3. Round | 09/08/2020 | CF Monterrey | - | Santos Laguna | 2:2 | ||||
| 4. Round | 14/08/2020 | CF América | - | Santos Laguna | 3:1 | ||||
| 5. Round | 17/08/2020 | Santos Laguna | - | Atlas Guadalajara | 0:0 | ||||
| 6. Round | 22/08/2020 | Club Necaxa | - | Santos Laguna | 2:1 | ||||
| 7. Round | 31/08/2020 | Santos Laguna | - | Gallos Blancos | 2:1 | ||||
| 11. Round | 20/09/2020 | Deportivo Toluca | - | Santos Laguna | 1:2 |
Mexico
Italy