| 2. Round | 24/07/2021 | FK Saturn | - | FK Kolomna | 3:0 | ||||
| 3. Round | 01/08/2021 | FK Kolomna | - | FK Khimki 2 | 0:3 | ||||
| 4. Round | 07/08/2021 | FK Strogino Moskva | - | FK Kolomna | 4:0 | ||||
| 7. Round | 29/08/2021 | FK Kolomna | - | FK Saransk | 1:4 |  |
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| 8. Round | 04/09/2021 | Kvant Obninsk | - | FK Kolomna | 2:0 |
Russia