| 11. Round | 28/11/2020 | SK Dnipro-1 | - | Shakhtar Donetsk | 0:1 | ||||
| 14. Round | 14/02/2021 | SK Dnipro-1 | - | Inhulets Petrove | 2:0 | ||||
| 15. Round | 22/02/2021 | Olimpik Donetsk | - | SK Dnipro-1 | 0:2 | ||||
| 16. Round | 27/02/2021 | FK Mariupol | - | SK Dnipro-1 | 2:2 | ||||
| 17. Round | 08/03/2021 | SK Dnipro-1 | - | FK Oleksandriya | 0:0 | ||||
| 18. Round | 13/03/2021 | Vorskla Poltava | - | SK Dnipro-1 | 0:1 | ||||
| 19. Round | 20/03/2021 | Desna Chernigov | - | SK Dnipro-1 | 0:2 | ||||
| 20. Round | 02/04/2021 | SK Dnipro-1 | - | FK Lviv | 5:1 | ||||
| 21. Round | 10/04/2021 | Dinamo Kiev | - | SK Dnipro-1 | 2:0 | ||||
| 22. Round | 18/04/2021 | Kolos Kovalivka | - | SK Dnipro-1 | 1:1 | ||||
| 23. Round | 24/04/2021 | SK Dnipro-1 | - | FC Mynai | 3:0 | ||||
| 24. Round | 01/05/2021 | Shakhtar Donetsk | - | SK Dnipro-1 | 2:1 | ||||
| 25. Round | 05/05/2021 | SK Dnipro-1 | - | Zorya Lugansk | 0:1 | ||||
| 26. Round | 09/05/2021 | SK Dnipro-1 | - | Rukh Lviv | 1:1 |
Ukraine