| 3. Round | 03/10/2020 | Cañoneros Marina | - | Cruz Azul Hidalgo | 0:4 |  |
|||
| 8. Round | 08/11/2020 | Cafessa Jalisco | - | Cañoneros Marina | 1:0 | ||||
| 9. Round | 16/11/2020 | Cañoneros Marina | - | Cafetaleros de Chiapas | 0:1 |  |
|||
| 10. Round | 21/11/2020 | Zitácuaro | - | Cañoneros Marina | 1:0 | ||||
| 11. Round | 28/11/2020 | Cañoneros Marina | - | Azores de Hidalgo | 2:3 | ||||
| 6. Round | 02/12/2020 | Aguacateros CDU | - | Cañoneros Marina | 3:0 | ||||
| 13. Round | 11/12/2020 | Cañoneros Marina | - | Club Irapuato | 1:2 | |
|||
| 16. Round | 30/01/2021 | Cruz Azul Hidalgo | - | Cañoneros Marina | 2:0 | ||||
| 17. Round | 05/02/2021 | Cañoneros Marina | - | CD Cuautla | 2:1 | |
|||
| 18. Round | 13/02/2021 | Deportivo Dongu | - | Cañoneros Marina | 4:2 | ||||
| 19. Round | 20/02/2021 | Cañoneros Marina | - | Aguacateros CDU | 0:4 |  |
|||
| 21. Round | 05/03/2021 | Cañoneros Marina | - | Cafessa Jalisco | 2:3 | ||||
| 23. Round | 20/03/2021 | Cañoneros Marina | - | Zitácuaro | 1:2 | ||||
| 14. Round | 25/03/2021 | Cañoneros Marina | - | Club de Ciervos | 0:1 | ||||
| 24. Round | 29/03/2021 | Azores de Hidalgo | - | Cañoneros Marina | 2:1 | ||||
| 26. Round | 09/04/2021 | Club Irapuato | - | Cañoneros Marina | 6:0 | |
Mexico