| 1. Round | 30/01/2023 | Club Olimpia | - | Sportivo Luqueño | 2:1 | ||||
| 5. Round | 26/02/2023 | Club Olimpia | - | Guaireña FC | 1:1 | ||||
| 6. Round | 04/03/2023 | Club Olimpia | - | Cerro Porteño | 2:2 |  |
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| 2. Round | 08/03/2023 | Club Nacional | - | Club Olimpia | 1:1 | ||||
| 7. Round | 12/03/2023 | General Caballero DJLM | - | Club Olimpia | 1:2 | ||||
| 8. Round | 19/03/2023 | Club Olimpia | - | Libertad | 2:1 | ||||
| 9. Round | 25/03/2023 | Sportivo Ameliano | - | Club Olimpia | 2:2 | ||||
| 10. Round | 01/04/2023 | Club Olimpia | - | Guaraní | 0:1 | |
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| 12. Round | 12/04/2023 | Sportivo Luqueño | - | Club Olimpia | 1:0 | ||||
| 13. Round | 16/04/2023 | Club Olimpia | - | Club Nacional | 0:1 | ||||
| 14. Round | 23/04/2023 | Tacuary | - | Club Olimpia | 0:1 | ||||
| 15. Round | 28/04/2023 | Club Olimpia | - | Sportivo Trinidense | 1:1 | |
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| 16. Round | 08/05/2023 | Guaireña FC | - | Club Olimpia | 1:0 | ||||
| 17. Round | 13/05/2023 | Cerro Porteño | - | Club Olimpia | 2:2 | |
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| 19. Round | 20/05/2023 | Libertad | - | Club Olimpia | 1:0 |
Argentina