| 16. Round | 18/07/2021 | FK Vitebsk | - | Neman Grodno | 2:0 | ||||
| 17. Round | 24/07/2021 | Neman Grodno | - | FK Slutsk | 1:0 | ||||
| 18. Round | 02/08/2021 | Dinamo Brest | - | Neman Grodno | 1:3 | ||||
| 20. Round | 22/08/2021 | FK Minsk | - | Neman Grodno | 0:4 | ||||
| 22. Round | 11/09/2021 | FK Isloch Minsk | - | Neman Grodno | 2:0 | ||||
| 23. Round | 19/09/2021 | Neman Grodno | - | FK Smorgon | 5:0 | ||||
| 24. Round | 26/09/2021 | Shakhter Soligorsk | - | Neman Grodno | 1:0 | ||||
| 25. Round | 01/10/2021 | Neman Grodno | - | Rukh Brest | 0:1 |
Russia