| 10. Round | 11/09/2021 | Spartak Moskva 2 | - | Volgar Astrakhan | 1:0 | ||||
| 11. Round | 15/09/2021 | Volgar Astrakhan | - | Alania Vladikavkaz | 1:1 | ||||
| 12. Round | 19/09/2021 | Tekstilshchik Ivanovo | - | Volgar Astrakhan | 1:2 | ||||
| 13. Round | 25/09/2021 | Volgar Astrakhan | - | Olimp-Dolgoprudny | 0:1 | ||||
| 14. Round | 29/09/2021 | SKA-Khabarovsk | - | Volgar Astrakhan | 1:0 | ||||
| 15. Round | 03/10/2021 | Volgar Astrakhan | - | Veles Moskva | 0:1 | ||||
| 22. Round | 13/11/2021 | Volgar Astrakhan | - | Rotor Volgograd | 2:0 |
Russia