| 1. Round | 29/01/2023 | Platense | - | Newell's Old Boys | 2:2 | ||||
| 2. Round | 03/02/2023 | Newell's Old Boys | - | Vélez Sarsfield | 1:0 | ||||
| 3. Round | 11/02/2023 | Defensa y Justicia | - | Newell's Old Boys | 1:0 | ||||
| 4. Round | 19/02/2023 | Newell's Old Boys | - | Banfield | 2:0 |  |
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| 6. Round | 05/03/2023 | Newell's Old Boys | - | Barracas Central | 1:0 | ||||
| 7. Round | 14/03/2023 | Colón de Santa Fe | - | Newell's Old Boys | 1:1 | ||||
| 8. Round | 20/03/2023 | Newell's Old Boys | - | San Lorenzo | 1:0 | ||||
| 9. Round | 31/03/2023 | Estudiantes | - | Newell's Old Boys | 3:0 | ||||
| 10. Round | 09/04/2023 | Newell's Old Boys | - | Rosario Central | 0:0 | ||||
| 11. Round | 12/04/2023 | Racing Club | - | Newell's Old Boys | 0:1 | ||||
| 12. Round | 16/04/2023 | Newell's Old Boys | - | River Plate | 0:1 | ||||
| 13. Round | 23/04/2023 | Belgrano de Córdoba | - | Newell's Old Boys | 1:0 | ||||
| 14. Round | 28/04/2023 | Newell's Old Boys | - | Argentinos Juniors | 0:0 |  |
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| 15. Round | 08/05/2023 | Tigre | - | Newell's Old Boys | 2:2 | |
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| 16. Round | 14/05/2023 | Newell's Old Boys | - | Arsenal de Sarandí | 2:0 | ||||
| 17. Round | 21/05/2023 | Lanús | - | Newell's Old Boys | 1:0 | ||||
| 18. Round | 29/05/2023 | Newell's Old Boys | - | Godoy Cruz | 2:0 |  |
Colombia