| 3. Round | 17/07/2022 | Pumas UNAM [U18] | - | Club Necaxa [U18] | 2:3 |  |
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| 4. Round | 22/07/2022 | Club Necaxa [U18] | - | FC Juárez [U18] | 3:0 | ||||
| 5. Round | 27/07/2022 | Club Necaxa [U18] | - | CF Pachuca [U18] | 1:2 |  |
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| 6. Round | 30/07/2022 | Cruz Azul [U18] | - | Club Necaxa [U18] | 0:5 | ||||
| 8. Round | 12/08/2022 | Club Necaxa [U18] | - | CF Monterrey [U18] | 1:1 | ||||
| 12. Round | 02/09/2022 | Club Necaxa [U18] | - | Club León [U18] | 1:1 | ||||
| 14. Round | 10/09/2022 | Club Necaxa [U18] | - | CF América [U18] | 0:4 |
Mexico