| 1. Round | 17/01/2020 | Guaraní | - | San Lorenzo | 0:0 |  |
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| 2. Round | 24/01/2020 | San Lorenzo | - | 12 de Octubre de Itauguá | 1:0 | ||||
| 3. Round | 01/02/2020 | Club Olimpia | - | San Lorenzo | 4:2 | ||||
| 4. Round | 08/02/2020 | San Lorenzo | - | Club Nacional | 1:1 | ||||
| 5. Round | 17/02/2020 | River Plate | - | San Lorenzo | 4:2 | ||||
| 17. Round | 31/08/2020 | Sportivo Luqueño | - | San Lorenzo | 0:0 | ||||
| 18. Round | 06/09/2020 | San Lorenzo | - | Sol de América | 1:1 | ||||
| 20. Round | 19/09/2020 | San Lorenzo | - | General Díaz | 2:1 | ||||
| 21. Round | 27/09/2020 | Libertad | - | San Lorenzo | 3:0 |
Paraguay