| 1. Round | 16/04/2022 | Manta FC [U19] | - | Atlético Santo Domingo [U19] | 0:1 | ||||
| 2. Round | 23/04/2022 | 9 de Octubre [U19] | - | Atlético Santo Domingo [U19] | 4:2 | ||||
| 3. Round | 07/05/2022 | Atlético Santo Domingo [U19] | - | Delfín SC [U19] | 0:0 | ||||
| 4. Round | 14/05/2022 | Emelec [U19] | - | Atlético Santo Domingo [U19] | 3:0 | ||||
| 7. Round | 10/07/2022 | Atlético Santo Domingo [U19] | - | 9 de Octubre [U19] | 3:0 | ||||
| 8. Round | 15/07/2022 | Delfín SC [U19] | - | Atlético Santo Domingo [U19] | 1:0 |
Ecuador