| 1. Round | 04/10/2020 | Honduras Progreso | - | Marathón | 1:1 | ||||
| 2. Round | 08/10/2020 | Honduras Progreso | - | Vida | 1:1 |  |
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| 3. Round | 12/10/2020 | Real España | - | Honduras Progreso | 5:0 | ||||
| 4. Round | 15/10/2020 | Platense | - | Honduras Progreso | 0:0 | ||||
| 5. Round | 19/10/2020 | Honduras Progreso | - | Lobos UPNFM | 2:3 | |
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| 7. Round | 25/10/2020 | Vida | - | Honduras Progreso | 4:1 | ||||
| 8. Round | 29/10/2020 | Honduras Progreso | - | Real España | 0:3 | ||||
| 9. Round | 01/11/2020 | Honduras Progreso | - | Platense | 1:1 | ||||
| 13. Round | 14/11/2020 | Honduras Progreso | - | Real Sociedad | 1:2 | |
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| 10. Round | 23/11/2020 | Lobos UPNFM | - | Honduras Progreso | 0:1 |  |
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| 12. Round | 29/11/2020 | Olimpia | - | Honduras Progreso | 5:0 | ||||
| 6. Round | 05/12/2020 | Marathón | - | Honduras Progreso | 4:0 |
Colombia