| 5. Round | 28/01/2025 | Santos Laguna [Women] | - | FC Juárez [Women] | 1:2 | ||||
| 11. Round | 11/03/2025 | Santos Laguna [Women] | - | Cruz Azul [Women] | 0:1 |  |
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| 12. Round | 15/03/2025 | UANL Tigres [Women] | - | Santos Laguna [Women] | 5:0 | ||||
| 13. Round | 19/03/2025 | Santos Laguna [Women] | - | CF Monterrey [Women] | 1:3 | ||||
| 14. Round | 23/03/2025 | Puebla FC [Women] | - | Santos Laguna [Women] | 2:1 | ||||
| 15. Round | 29/03/2025 | Santos Laguna [Women] | - | CF América [Women] | 0:3 | ||||
| 16. Round | 15/04/2025 | Club León [Women] | - | Santos Laguna [Women] | 3:1 | ||||
| 17. Round | 18/04/2025 | Mazatlán FC [Women] | - | Santos Laguna [Women] | 1:2 |
Mexico