| 1. Round | 30/07/2022 | Rentistas | - | Albion | 2:4 |  |
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| 2. Round | 08/08/2022 | Albion | - | Liverpool | 1:1 | ||||
| 3. Round | 13/08/2022 | Peñarol | - | Albion | 2:0 | ||||
| 6. Round | 22/08/2022 | Albion | - | Plaza Colonia | 1:0 | ||||
| 5. Round | 27/08/2022 | Montevideo Wanderers | - | Albion | 0:0 | ||||
| 4. Round | 03/09/2022 | Albion | - | Montevideo City Torque | 1:0 | ||||
| 7. Round | 10/09/2022 | Boston River | - | Albion | 1:0 | ||||
| 8. Round | 14/09/2022 | Albion | - | River Plate | 0:2 | ||||
| 9. Round | 18/09/2022 | Cerro Largo | - | Albion | 1:2 | |
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| 11. Round | 02/10/2022 | Defensor Sporting | - | Albion | 2:0 | ||||
| 12. Round | 08/10/2022 | Cerrito | - | Albion | 0:0 |  |
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| 14. Round | 16/10/2022 | Danubio | - | Albion | 3:0 | ||||
| 15. Round | 24/10/2022 | Albion | - | Deportivo Maldonado | 1:3 |
Uruguay