| 18. Round | 12/01/2025 | FC Twente | - | Willem II | 6:2 | ||||
| 19. Round | 18/01/2025 | Willem II | - | Feyenoord | 1:1 | ||||
| 20. Round | 26/01/2025 | RKC Waalwijk | - | Willem II | 2:0 | ||||
| 23. Round | 15/02/2025 | Willem II | - | FC Groningen | 1:3 | ||||
| 25. Round | 09/03/2025 | Willem II | - | FC Utrecht | 2:3 | ||||
| 26. Round | 16/03/2025 | Go Ahead Eagles | - | Willem II | 1:0 | ||||
| 27. Round | 29/03/2025 | Willem II | - | Almere City FC | 0:2 |  |
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| 28. Round | 04/04/2025 | sc Heerenveen | - | Willem II | 3:1 | ||||
| 29. Round | 13/04/2025 | Willem II | - | AFC Ajax | 1:2 | ||||
| 30. Round | 27/04/2025 | Fortuna Sittard | - | Willem II | 1:0 | ||||
| 32. Round | 09/05/2025 | Willem II | - | Heracles Almelo | 1:2 | ||||
| 33. Round | 14/05/2025 | Willem II | - | PEC Zwolle | 1:2 |
Belgium