| 1. Round | 06/02/2023 | Plaza Colonia | - | Deportivo Maldonado | 0:1 | ||||
| 2. Round | 11/02/2023 | River Plate | - | Plaza Colonia | 2:0 | ||||
| 3. Round | 18/02/2023 | Plaza Colonia | - | Nacional | 2:1 | ||||
| 4. Round | 26/02/2023 | Danubio | - | Plaza Colonia | 5:0 | ||||
| 6. Round | 11/03/2023 | Montevideo Wanderers | - | Plaza Colonia | 0:1 | ||||
| 7. Round | 17/03/2023 | Plaza Colonia | - | La Luz | 1:1 | ||||
| 8. Round | 25/03/2023 | Defensor Sporting | - | Plaza Colonia | 4:0 | ||||
| 9. Round | 03/04/2023 | Plaza Colonia | - | Montevideo City Torque | 1:2 | ||||
| 10. Round | 10/04/2023 | Liverpool | - | Plaza Colonia | 3:1 | ||||
| 11. Round | 16/04/2023 | Plaza Colonia | - | Cerro Largo | 2:0 | ||||
| 12. Round | 23/04/2023 | Plaza Colonia | - | Peñarol | 1:2 | ||||
| 13. Round | 03/05/2023 | Racing | - | Plaza Colonia | 1:1 | ||||
| 14. Round | 08/05/2023 | Plaza Colonia | - | CA Cerro | 1:1 | ||||
| 15. Round | 15/05/2023 | Boston River | - | Plaza Colonia | 1:1 |  |
Uruguay