| 1. Round | 07/03/2016 | Seattle Sounders | - | Sporting Kansas City | 0:1 | ||||
| 1. Round | 12/03/2016 | Real Salt Lake | - | Seattle Sounders | 2:1 |  |
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| 1. Round | 20/03/2016 | Seattle Sounders | - | Vancouver Whitecaps | 1:2 | ||||
| 2. Round | 30/04/2016 | Seattle Sounders | - | Columbus Crew | 1:0 | ||||
| 3. Round | 22/05/2016 | Seattle Sounders | - | Colorado Rapids | 0:1 | ||||
| 3. Round | 29/05/2016 | New England Revolution | - | Seattle Sounders | 2:1 | ||||
| 4. Round | 02/06/2016 | D.C. United | - | Seattle Sounders | 0:2 | ||||
| 5. Round | 03/07/2016 | Toronto FC | - | Seattle Sounders | 1:1 | ||||
| 5. Round | 09/07/2016 | Seattle Sounders | - | Los Angeles Galaxy | 0:1 | ||||
| 5. Round | 24/07/2016 | Sporting Kansas City | - | Seattle Sounders | 3:0 | ||||
| 6. Round | 08/08/2016 | Orlando City | - | Seattle Sounders | 1:3 | |
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| 6. Round | 25/08/2016 | Houston Dynamo | - | Seattle Sounders | 1:1 | ||||
| 8. Round | 16/10/2016 | FC Dallas | - | Seattle Sounders | 2:1 |
USA